Search
Nota: questa è una simulazione grafica del profilo LinkedIn revisionato. I contenuti sono pensati per mostrare il nuovo posizionamento professionale e potranno essere adattati prima della pubblicazione effettiva.
iPSC-based Disease Modeling RNA Biology · Neuroscience · Rare Diseases · Translational Research
SA

Simone Alberti, PhD

Postdoctoral Scientist | iPSC-based Disease Modeling, RNA Biology & Neuroscience | Translational Research / R&D | Rare Diseases

Milan, Lombardy, Italy · Contact info

Open to opportunities in Europe, Switzerland and the Nordic life science ecosystem

ORCID: 0009-0006-6839-4773 · linkedin.com/in/simonealberti1

Ospedale San Raffaele
Università Vita-Salute San Raffaele

Open to work

R&D Scientist, Research Scientist, Translational Research Scientist, Postdoctoral Researcher, Scientist roles

Europe · Switzerland · Denmark · Copenhagen · Netherlands · Belgium · Italy
See all details

Analytics

Private to you

132 profile views Discover who’s viewed your profile.
48 search appearances See how often you appear in search results.
15 post impressions Start sharing scientific updates to increase visibility.

Resources

Private to you

Creator mode Suggested focus: iPSC models · RNA biology · neuroscience · rare diseases · R&D
My network Recommended: researchers, biotech recruiters, R&D managers, PIs and Medical Affairs professionals.

About

I am a PhD-trained biotechnologist and postdoctoral scientist with a background in Molecular Medicine, currently working in neuroscience research at Ospedale San Raffaele in Milan.

My work focuses on iPSC-based disease modeling, RNA biology and neurodevelopmental disorders, with experience in human iPSC-derived neuronal models, Prader-Willi Syndrome, Rett Syndrome and tauopathy-related research. I am particularly interested in how advanced in vitro models can help investigate disease mechanisms and support the development of future therapeutic strategies.

During my PhD, I independently managed a research project on Prader-Willi Syndrome, focusing on the role of the non-coding RNA SNORD116 using human iPSC-derived neurons. This experience allowed me to work across the full research process: literature analysis, hypothesis generation, experimental design, protocol optimization, data interpretation and scientific discussion.

My core technical expertise includes iPSC culture and neuronal differentiation, RNA Immunoprecipitation, RNA extraction, qRT-PCR, molecular cloning, blotting techniques and imaging-based assays. I also value scientific communication and enjoy presenting data, discussing research questions and translating complex findings into clear scientific narratives.

I am now exploring opportunities in R&D, translational research and biotech/pharma environments, particularly in Europe, Switzerland and the Nordic life science ecosystem. I am also interested in future paths at the interface between science, clinical evidence and medical communication, including Medical Affairs / MSL-related roles.

Featured

ORCID
Scientific profile ORCID profile and research identity 0009-0006-6839-4773
PhD
PhD research focus Human iPSC-derived neurons for the study of Prader-Willi Syndrome iPSC · SNORD116 · RNA Biology
R&D
Research interests iPSC disease modeling, neuroscience, rare diseases and translational research Europe · Copenhagen · Switzerland

Activity

Suggested first post

SA
Simone Alberti, PhD Postdoctoral Scientist · iPSC-based Disease Modeling

During my PhD in Molecular Medicine, I worked on human iPSC-derived neuronal models to investigate Prader-Willi Syndrome, with a specific focus on the non-coding RNA SNORD116.

This experience taught me that research is not only about applying protocols, but also about learning how to move through uncertainty: reading the literature critically, designing experiments, interpreting complex data and building hypotheses when the path is not already defined.

I am particularly interested in how iPSC-based disease models and RNA biology can help us better understand neurodevelopmental and rare diseases, and potentially support the development of future therapeutic strategies.

I am now exploring opportunities in R&D, translational research and biotech/pharma environments, especially in Europe and the Nordic life science ecosystem.

Like Comment Repost Send

Experience

Postdoctoral Researcher

Ospedale San Raffaele · Full-time

2026 – Present · Milan, Italy

Working on in vitro models of neurodevelopmental and neurodegenerative disorders, with a focus on iPSC-derived neuronal systems and RNA-focused molecular biology.

  • Developing and maintaining human iPSC-derived neuronal models to investigate disease-relevant mechanisms.
  • Conducting molecular biology experiments related to RNA biology, including RNA Immunoprecipitation, RNA extraction and qRT-PCR.
  • Contributing to in vitro studies related to Rett Syndrome and Alzheimer’s disease / tauopathy-related research.
  • Designing and executing experiments independently, from literature review and hypothesis generation to protocol optimization and data interpretation.
  • Presenting and discussing experimental results in internal scientific meetings.

PhD Researcher in Molecular Medicine – Neuroscience

Università Vita-Salute San Raffaele / Ospedale San Raffaele

2022 – 2026 · Milan, Italy

PhD project focused on human iPSC-derived neurons for the study and treatment of Prader-Willi Syndrome, with particular attention to the functional role of the non-coding RNA SNORD116.

  • Independently managed a complex research project on Prader-Willi Syndrome using human iPSC-derived neuronal models.
  • Generated and differentiated iPSCs into neuronal cells to investigate disease mechanisms.
  • Optimized an RNA Immunoprecipitation protocol to study potential SNORD116 interactors.
  • Applied molecular biology techniques including RNA/DNA/protein extraction, qRT-PCR, PCR, molecular cloning and blotting.
  • Combined scientific literature review, experimental design and data interpretation to develop coherent research hypotheses.

Master Thesis Researcher

Viral Pathogens and Biosafety Unit · Università Vita-Salute San Raffaele

2019 – 2022 · Milan, Italy

Master’s thesis focused on the development of a microneutralization assay to test molecules capable of blocking the entry of SARS-CoV-2 variants into target cells.

  • Worked on in vitro experimental approaches related to SARS-CoV-2 Spike protein-containing viral models.
  • Developed experience in assay-based research and experimental validation.
  • Strengthened technical skills in cell-based assays, molecular biology and data interpretation.

Education

PhD in Molecular Medicine – Neuroscience

Università Vita-Salute San Raffaele

2022 – 2026 · Graduated with honors

Thesis: Stem cell-based models of Prader-Willi Syndrome to elucidate new functions and interactors of SNORD116.

M.Sc. in Biotechnology and Medical Biology

Università Vita-Salute San Raffaele

2019 – 2022 · 110/110 cum laude

Thesis: Inhibition of non-replicating SARS-CoV-2 Spike protein-containing virus infection by extracellular vesicles.

B.Sc. in Medical and Pharmaceutical Biotechnology

Università Vita-Salute San Raffaele

2016 – 2019 · 110/110

Literature review thesis: Kynurenine pathway in schizophrenia.

Skills

iPSC-based disease modeling Core scientific expertise
RNA Biology Core scientific expertise
RNA Immunoprecipitation Laboratory technique
Neuronal Differentiation Laboratory technique
Scientific Communication Transferable skill
iPSC Culture Laboratory technique
Stem Cell Biology Core scientific expertise
Neuroscience Core scientific expertise
Neurodevelopmental Disorders Core scientific expertise
Rare Diseases Core scientific expertise
Molecular Medicine Core scientific expertise
Translational Research Research positioning
In vitro Disease Models Core scientific expertise
SNORD116 Research Research focus
Prader-Willi Syndrome Research focus
Rett Syndrome Models Research area
Tauopathy-related Research Research area
RNA Extraction Laboratory technique
DNA Extraction Laboratory technique
Protein Extraction Laboratory technique
qRT-PCR Laboratory technique
PCR Laboratory technique
Molecular Cloning Laboratory technique
Western Blot Laboratory technique
Northern Blot Laboratory technique
Southern Blot Laboratory technique
RNAScope In Situ Hybridization Laboratory technique
Immunofluorescence Laboratory technique
Confocal Microscopy Imaging technique
Widefield Microscopy Imaging technique
Luciferase Assay Laboratory technique
Transfection Cellular engineering
Transduction Cellular engineering
Lentivirus Production Cellular engineering
Experimental Design Transferable skill
Data Interpretation Transferable skill
Scientific Literature Review Transferable skill
Protocol Optimization Transferable skill
Problem Solving Transferable skill
Scientific Writing Transferable skill
Cross-functional Collaboration Transferable skill
Presentation Skills Transferable skill

Recommendations

Professional reviews and scientific references

PI
Research Supervisor Principal Investigator · Neuroscience Research

Simone has shown strong autonomy in managing complex experimental questions, especially in the context of iPSC-derived neuronal models and RNA-focused molecular biology. His ability to connect scientific literature, experimental design and data interpretation makes him a solid profile for research environments where critical thinking and resilience are essential.

Sample recommendation · to be replaced with real text
CL
Research Collaborator Academic Partner · Molecular Biology

Working with Simone means working with someone who approaches scientific problems with precision, curiosity and persistence. He is able to discuss complex biological questions clearly and contribute constructively to experimental planning and interpretation.

Sample recommendation · to be replaced with real text
JR
Junior Researcher / Lab Colleague Stem Cell and Neurogenesis Unit

Simone combines solid technical expertise with a genuine interest in explaining science and sharing knowledge. His experience with iPSC culture, neuronal differentiation and RNA biology makes him a valuable colleague in projects requiring accuracy, patience and scientific discussion.

Sample recommendation · to be replaced with real text